Quantum-enhanced nanodiamond rapid test advances early SARS-CoV-2 antigen detection in clinical diagnostics

Alyssa Thomas DeCruz; Benjamin S. Miller; Da Huang; Max McRobbie; Felix Donaldson; Laura E. McCoy; Ciara K. O’Sullivan; Johannes C. Botha; Eleni Nastouli; Rachel A. McKendry

doi:10.1038/s41467-025-63066-1

Quantum-enhanced nanodiamond rapid test advances early SARS-CoV-2 antigen detection in clinical diagnostics

Alyssa Thomas DeCruz, Benjamin S. Miller, Da Huang, Max McRobbie, Felix Donaldson, Laura E. McCoy, Ciara K. O’Sullivan, Johannes C. Botha, Eleni Nastouli, Rachel A. McKendry

2025Nature Communications 16, 8778CC BY 4.0LCP000075

Fig. 2, panel (b)

Panel (b): normalised lock-in signal (log) against recombinant nucleocapsid concentration (M) for the FND assay with modulation (blue) and 40 nm gold nanoparticles (teal): mean and SD (circles, n = 3 tests), replicate rows (crosses), exponential fit with 95% band, LoD (solid) and its 95% CI (dotted). Blanks at zero concentration are in the data but not drawn on the log axis.

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This panel was computed from the authors' public data deposit (Nature Communications Source Data: https://doi.org/10.1038/s41467-025-63066-1, CC BY 4.0). The plot shown here is re-rendered for interactive viewing and analysis. See the paper for the original figure and full scientific context.

License: CC BY 4.0.

Nat. Commun. 16, 8778 (2025) · DOI: 10.1038/s41467-025-63066-1

Other panels of Fig. 2: (a) (c) (d)

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